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Police have confirmed a “number of fatalities” and injuries following a "serious incident" at an arena where an Ariana Grande concert was being held.

(ZH) Update 3: BBC is reporting that authorities are treating the explosion as a terror incident.

"We were making our way out and when we were right by the door there was a massive explosion and everybody was screaming," Catherine Macfarlane told Reuters.

"It was a huge explosion - you could feel it in your chest. It was chaotic. Everybody was running and screaming and just trying to get out of the area."

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Update 2: NBC News confirms the BBC's report that there are at least 20 dead - Eye witness on BBC says 20 to 30 people injured and dead in the box office area of Manchester Arena.

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The explosions can be heard in the following clip... (around 7 seconds in - look to the far left and notice the sudden light also)

Members of the public have been advised to avoid the arena. One Twitter user wrote: "Honestly worst night of my existence. Just kept running from Manchester Arena for my life." Another added: “Just got out of Manchester arena after seeing Ariana perform. There was a loud bang when the lights came on & everyone ran out screaming.” Live feed here: Here are videos of the scene from just after the explosion: